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Home > Products >  High purity Pyrimethamine for antifungal drugs with good quality

High purity Pyrimethamine for antifungal drugs with good quality CAS NO.58-14-0

  • FOB Price: USD: 1.00-1.00 /Gram Get Latest Price
  • Min.Order: 1 Gram
  • Payment Terms: T/T,
  • Available Specifications:

    1(1-10)Gram

  • Product Details

Keywords

  • Pyrimethamine
  • purity 99% Pyrimethamine
  • 58-14-0

Quick Details

  • ProName: High purity Pyrimethamine for antifung...
  • CasNo: 58-14-0
  • Molecular Formula: C12H13ClN4
  • Appearance: White crystallized powder
  • Application: Pharmaceutical Raw Materials
  • DeliveryTime: within 7 working days
  • PackAge: al foil bag
  • Port: shanghai
  • ProductionCapacity: 1000 Kilogram/Month
  • Purity: 99% min
  • Storage: Kept in a well-closed, light-resistan...
  • Transportation: Kept in a well-closed, light-resistan...
  • LimitNum: 1 Gram
  • Molecular Formula: C12H13ClN4
  • Impurity: 0.05%

Superiority

1, High quality with competitive price: 
1)Purity≥ 99% 
2)We are manufacturer and can provide high quality products with factory price,offering free samples to test, a few shipping fee only.

 

2.Flexible Payment term
1).we accept every payment term as if you could imagine,such as T/T, Paypal, Money Gram, , Bank transfer.
2).we also offer Bitcoin as a payment to your honor.like Australia,Canada.

 

3, Fast and safe delivery 
1)Parcel can be sent out in 24 hours after payment. Tracking numbers available 
3)Secure and discreet shipment. Various transportation methods for your choice.
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring. 
5)We have special way could ship 0.01kg to sveral kg products a time. We offer melting powder into liquid service. And ship the liquid in special bottles.
6)Offer the latest tracking number for you to check

 

4, We have clients throughout the world. 
1)Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire. 
2)Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility. 
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

 

5. Good after-sales service.
1)Tell the package update ASAP, and will try best solve when customer encountered various problems.
2)we will teach you recipes and instructions for all kind of steroid to turn powder into liquid, and liquid become sterile ones.

 

Details

Details

High purity Pyrimethamine for antifungal drugs with good quality

 

basic information

product name:

pyrimethamine

synonyms:

2,4-diamino-5-(4-chlorophenyl)-6-ethylpyrimidine;2,4-diamino-5-chlorophenyl-6-ethylpyrimidine;2,4-pyrimidinediamine, 5-(4-chlorophenyl)-6-ethyl-;2,4-pyrimidinediamine, 5-(p-chlorophenyl)-6-ethyl-;2,4-pyrimidinediamine,5-(4-chlorophenyl)-6-ethyl-;4753 r.p.;4753r.p.;5-(4’-chlorophenyl)-2,4-diamino-6-ethylpyrimidine

cas:

58-14-0

mf:

c12h13cln4

mw:

248.71

product categories:

apis & intermediate;pyrimidine;organics;amines;bases & related reagents;heterocycles;intermediates & fine chemicals;nucleotides;pharmaceuticals;inhibitor;heterocycle-pyrimidine series;daraprim

mol file:

58-14-0.mol

pyrimethamine structure

 

chemical properties

melting point

233-234°c

boiling point

491.5 °c at 760 mmhg

density

1.305 g/cm3

flashing point

251 °c

vapor pressure

8.34e-10 mmhg at 25°c

storage temp.

0-6°c

water solubility

<0.01 g/100 ml at 21 ºc

stability

stable, but light sensitive. combustible. incompatible with strong oxidizing agents.

 

usage and synthesis

chemical properties

white solid

usage

dihydrofolate reductase inhibitor; generally used in combination with other antimicrobial agents. antiprotozoal (toxoplasma); antimalarial

for the treatment of toxoplasmosis and acute malaria; for the prevention of malaria in areas non-resistant to pyrimethamine

air & water reactions

insoluble in water.

reactivity profile

pyrimethamine is sensitive to exposure to light . neutralizes acids to form salts plus water in exothermic reactions. may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

fire hazard

flash point data for pyrimethamine are not available; however, pyrimethamine is probably combustible.

biological activity

potent inhibitor of multi-drug and toxin extrusion (mate) transporters (k i values are 46 and 77 nm for human mate2-k-hek293 and mate1-hek293 cells respectively). also inhibits dihydrofolate reductase (dhfr).

 

 

 

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