High purity Sorafenib tosylate for Advanced liver cancer treatment CAS NO.475207-59-1
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- Min.Order: 1 Gram
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1(1-10)Gram
- Product Details
Keywords
- Sorafenib tosylate
- 475207-59-1
- purity 99% Sorafenib tosylate
Quick Details
- ProName: High purity Sorafenib tosylate for Adv...
- CasNo: 475207-59-1
- Molecular Formula: C21H16ClF3N4O3·C7H8SO3
- Appearance: White crystallized powder
- Application: medical
- DeliveryTime: within 7 working days
- PackAge: al foil bag
- Port: shanghai
- ProductionCapacity: 1000 Kilogram/Month
- Purity: 99% min
- Storage: Kept in a well-closed, light-resistan...
- Transportation: Kept in a well-closed, light-resistan...
- LimitNum: 1 Gram
- Molecular Formula: C21H16ClF3N4O3·C7H8SO3
- Impurity: 0.05%
Superiority
1, High quality with competitive price:
1)Purity≥ 99%
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Details
Details
Basic information
Product Name: |
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Synonyms: |
SORAFENIB TOSYLATE;Sorafenib & its intermediates;Sorafinib mesylate;4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide monomethanesulfonate;Sorafenib Tosylate(Bay 43-9006,Nexavar);2-PyridinecarboxaMide, 4-[4-[[[[4-chloro-3-(trifluoroMethyl)phenyl]aMino]carbonyl]aMino]phenoxy]-N-Methyl-, 4-Methylbenzenesulfonate;Sorafenib Tosylate (Nexavar);Sorafenib (Nexavar) |
CAS: |
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MF: |
C21H16ClF3N4O3.C7H8SO3 |
MW: |
637.03 |
Product Categories: |
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Chemical Properties |
melting point |
242-245℃ |
boiling point |
523.3 °C at 760 mmHg |
density |
1.454 g/cm3 |
flashing point |
270.3 °C |
vapor pressure |
4.76E-11 mmHg at 25°C |
Usage And Synthesis |
Usage |
Sorafenib Tosylate (Bay 43-9006, Nexavar) is a small molecular inhibitor of VEGFR, PDGFR, c-Raf and B-Raf with IC50s of 18 nM, 10 nM, 3 nM and 15 nM, respectively. |
Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively |
Description:
This peptide hormone, called alpha-Melanocyte stimulating hormone or MSH, activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan 2 has been shown in studies to exhibit appetite suppressant, lipolytic, and libido-enhancing effects in addition to promoting skin tanning.
Applications:
Testosterone Acetate combination of Testosterone and ester acetate, Testosterone Acetate is an androgenic steroide with a pronounced anabolic effect. Most acetate treatments deliver medication to the body relatively quickly.
Testosterone Acetate has very low risk of water retention. Individuals that utilize this form of Testosterone also claim that it is arguably the most painless form of Testosterone. Testosterone Acetate ester is much faster acting, and thus requires a more frequent schedule in order to keep blood levels as stable as possible.
Testosterone Acetate Results of Analysis:
Test Items |
Specification |
Test Results |
Appearance |
White or almost white crystalline powder |
white crystalline powder |
Loss on drying |
≦0.5% |
0.34% |
Melting point |
139-141 °C |
139-140 °C |
(HPLC)Assay |
97-103.0% |
99.08% |
Free acid |
0.5%max |
0.31% |
Conclusion |
The aboye product conforms analysis standard |
Conform |