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Home > Products >  Safe Delivery Adrenocortical Hormone Raw Materials Hydrocortisone Acetate with Strong Effect

Safe Delivery Adrenocortical Hormone Raw Materials Hydrocortisone Acetate with Strong Effect CAS NO.50-03-3

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Keywords

  • Hydrocortisone acetate
  • 50-03-3
  • Hydrocortisone acetate powder

Quick Details

  • ProName: Safe Delivery Adrenocortical Hormone R...
  • CasNo: 50-03-3
  • Molecular Formula: C23H32O6
  • Appearance: White crystallized powder
  • Application: Pharmaceutical Material
  • DeliveryTime: within 7 working days
  • PackAge: al foil bag
  • Port: shanghai
  • ProductionCapacity: 1000 Kilogram/Month
  • Purity: 99% min
  • Storage: Kept in a well-closed, light-resistan...
  • Transportation: Kept in a well-closed, light-resistan...
  • LimitNum: 1 Gram
  • Molecular Formula: C23H32O6
  • Impurity: 0.05%

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Details

 

Details

Safe Delivery Adrenocortical Hormone Raw Materials Hydrocortisone Acetate with Strong Effect

Product Name: Hydrocortisone acetate
Synonyms: (11beta)-21-(Acetoxy)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione;11,17-Dihydroxy-3,20-dioxopregn-4-en-21-yl acetate;11-beta,17-alpha-dihydroxy-21-acetoxypregesterone;11beta17alpha-Dihydroxy-21-acetoxypregesterone;17-alpha-hydrocorticosterone21-acetate;17alpha-Hydrocorticosterone-21-acetate;17-dihydroxy-20-dion(11-beta)-pregn-4-ene-21-(acetoxy)-11;17-dihydroxy-20-dion(11beta)-pregn-4-ene-21-(acetyloxy)-11
CAS: 50-03-3
MF: C23H32O6
MW: 404.5
EINECS: 200-004-4
Product Categories: Biochemistry;Hydroxyketosteroids;Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;Veterinaries;Steroid and Hormone;Hormone Drugs;Adrenal cortical hormone drugs;API
Mol File: 50-03-3.mol
Hydrocortisone acetate Structure
 
Hydrocortisone acetate Chemical Properties
Melting point 223 °C (dec.)(lit.)
Fp 223°C
storage temp. 0-6°C
Decomposition 223 ºC
Merck 14,4787
BRN 2066841
Stability: Stable, but may be light or moisture sensitive. Incompatible with strong oxidizing agents.
CAS DataBase Reference 50-03-3(CAS DataBase Reference)
NIST Chemistry Reference ALFA English
 
Hydrocortisone acetate Usage And Synthesis
Adrenocorticotropic hormone drugs Hydrocortisone acetate is an adrenal hormone drugs, white crystalline powder, odorless, bitter taste. The melting point is 216 ~ 222 ℃, right optical. Slightly soluble in ethanol, ether, chloroform, acetone, insoluble in water. It was synthesized by In 17α- hydroxy progesterone. 
Hydrocortisone acetate has important physiological activities such as anti-inflammatory, anti-viral, anti-allergic, anti-shock, reducing inflammatory exudation effect, commonly used in clinical adrenal insufficiency and autoimmune diseases. Preparations are injection, tablets, ointments and eye drops. Adding a small amount of hydrocortisone acetate in some cosmetics cortisol can increase the efficacy of anti-allergy and improve the degree of whitening of the skin, but long-term using of such substances can cause the skin produce hormone-dependent disease. Our cosmetics cosmetics specifications prescribedthathormone substances can not be added.
Indications For allergic, non-infectious skin diseases and a number of proliferative skin disorders. Such as dermatitis, eczema, neurodermatitis, seborrheic dermatitis and itching psychosis.

Figure 1 the chemical structure formula of tetra-fluoroethane.
Contraindications 1. This medicine and matrix components allergy and allergic to other glucocorticoids are prohibited.
2. The primary bacterial, fungal and viral infectious skin diseases such as disabledare prohibited.
The above information is edited by the chemicalbook of KuiMing.
Adverse Reactions Long-term using can cause local skin atrophy, telangiectasia, pigmentation, folliculitis, perioral dermatitis and secondary infection.
Precautions 1. Not long-term, large-scale use. 
2. The coated parts such as a burning sensation, itching, swelling, etc., should stop the medication.
Chemical Property White or almost white crystalline powder, odorless. Mp218-221.5 ℃; 25D + 166 ° (dioxane) Specific rotation [α]; ethanol maximum absorption at 240nm wavelength. Insoluble in water, slightly soluble in ethanol (1: 230) and chloroform (1: 150), insoluble in ether.
Uses Corticosteroid drugs, have anti-inflammatory, anti-allergic, anti-toxins, anti-shock effect.
Production methods Hydrocortisone and acetic anhydride in pyridine esterification.
Chemical Properties white powder
Usage Glucocorticoid
 
Hydrocortisone acetate Preparation Products And Raw materials
Raw materials Azabenzene-->Hydrocortisone-->Saponin

Package Specification: 25 Kg/Drum 10 Kg/Drum 5 Kg/Drum

Quality Specification: EP/USP/Ch.P/JP

 
 
 
 

 

 

 

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